Print Page | Contact Us | Sign In | Register
Upcoming Meeting Information
Share |


The Toxicology Forum is hosting a series of virtual sessions to facilitate dialogue and information exchange among presenters, panelists, and attendees.

 

  Register Here

 

Registration is required for these virtual sessions. Registration is all inclusive and attendees may attend any of the scheduled virtual sessions.

How will the virtual sessions function? Dialogue among presenters and attendees is a pillar of Toxicology Forum Meetings. In these virtual sessions, attendees will be able to contribute to the live discussion(s), ask questions, share their views, and participate in live polling and chat throughout the session.

Your voice and viewpoints drive the dialogue and we look forward to your continued contributions!

 

Upcoming Virtual Sessions

 

New approach methodologies (NAMs) offer great promise to improve human health risk assessment by centering on human biology, reducing the need to extrapolate from animal-based toxicity testing results. As NAMs are being accepted into health authority and regulatory decision-making as screening and prioritization tools, there is also interest in leveraging NAMs for quantitative risk assessment purposes. One of the acknowledged limitations of NAMs is their current inability to wholly reflect the complexity of biology, such as the impact of compensatory mechanisms. This session will address ongoing work in this area using systems-based approaches to identify adverse outcomes derived from NAMs. Two presentations from government and industry will discuss the concept of toxicological tipping points between adaptive and adverse responses, and comprehensive cellular stress panels integrated with probabilistic models and toxicokinetic considerations. Based on these advanced approaches it could be argued that NAMs deserve a more prominent role in risk assessment beyond their current accepted uses as screening and prioritization tools, provided exposure can also be effectively incorporated. These presentations will be complemented with another conversation on how health authorities are integrating NAMs into their decisions of potential endocrine disruption. A potential framework of how this Next Generation Risk Assessment could be achieved will also be shared and discussed. This multi-sector approach to better understanding the utility and opportunities of NAMs in risk assessment will support a risk-based approach to regulatory decision while still leveraging the cutting-edge technologies afforded by these advancements.

Presentation Schedule

Can We Identify Tipping Points between Adaptive and Adverse Perturbations from In Vitro Data?
Imran Shah, US EPA

Implementation of NAMs in a Next Generation Risk Assessment
Maria Baltazar, Unilever

Integration of NAM Data to Identify Chemicals with Endocrine Disruptor Properties under ECHA/EFSA Guidance 
Susan Borghoff, ToxStrategies Inc.

Moderated Panel Discussion
Additional Panelists:
Suzanne Fitzpatrick, US FDA/CFSAN
William Irwin, US EPA

Moderators: Phillip Wages, PepsiCo; Nicole Kleinstreuer, NIEHS/NICEATM


 

Please be sure to register in advance for the webinars. Registration is all inclusive for the three webinars.

 

Registration Fees:

Member: $100
Nonmember: $150

Registrants will receive an email with access information for each webinar in advance of the scheduled webinar date.

 

Important: If you have never joined an Event using Cisco WebEx, please take a minute and download the needed software in advance to ensure a seamless connection process.

PC: https://akamaicdn.webex.com/client/WBXclient-40.4.12-8/webexapp.msi

Mac: https://akamaicdn.webex.com/client/WBXclient-40.4.12-8/mac/intel/webexec_intel.dmg

 

Attendee Participation Details: The virtual sessions are held via Cisco WebEx. Attendees will be able to contribute verbally during the panel discussions and Q/A time after each presentation. Session chairs will call on individuals raising their hands to share their views and ask questions.

In addition to scientific presentations and the panel discussions, session organizers are working to integrate interactive polling and chat questions to help increase opportunities for dialogue and understanding among attendees. 

 

Questions: Please contact Kevin Merritt at The Toxicology Forum, either via email or phone {1.703.547.0876} with any questions or concerns about the virtual sessions.