This website uses cookies to store information on your computer. Some of these cookies are used for visitor analysis, others are essential to making our site function properly and improve the user experience. By using this site, you consent to the placement of these cookies. Click Accept to consent and dismiss this message or Deny to leave this website. Read our Privacy Statement for more.
Print Page | Contact Us | Sign In | Register
2020 Winter Meeting Agenda

44th Annual Winter Meeting—Detailed Agenda 

Program Planning Committee Members


Brian Hughes, NSF International (Chair)
Grace Chappell, ToxStrategies, Inc. (Co-Chair)

Tracy Chen, US FDA
Weihsueh Chiu, Texas A&M University
Laurie Dolan, GRAS Associates
Allison Harrill, NIEHS
Esther Haugabrooks, Physician's Council for Responsible Medicine
Jessica Lyn LaRocca, Corteva Agriscience
Santhini Ramasamy, US EPA/NCEA
Reza Rasoulpour, Corteva Agriscience 
Satinder Sarang, Shell International


Detailed Program Schedule By Day



Monday, January 27


8:00 AM–12:00 Noon

Session: Use of New Approach Methodologies in Risk Characterization of PFAS: Challenges and Opportunities

Michael DeVito, US EPA/CCTE
Laurie Haws, ToxStrategies, Inc.

8:00 AM–8:05 AM

Introduction to the Session

Laurie Haws, ToxStrategies, Inc.

8:05 AM–8:20 AM

Issues That the US FDA Is Facing in Terms of PFAS Compounds in Foods

David Goldman, US FDA

8:20 AM–8:35 AM

Issues That the US EPA Is Facing in Terms of PFAS Compounds in the Environment

Bruce Rodan, US EPA

8:35 AM–9:05 AM

A Chemical Category-Based Approach for Selecting and Screening PFAS for Toxicity and Toxicokinetic Testing

Grace Patlewicz, US EPA/CCTE

9:05 AM–9:35 AM

Use of High-Throughput Toxicity Testing to Assess PFAS  

Michael DeVito, US EPA/CCTE

9:35 AM–10:05 AM

Application of High-Throughput Toxicokinetics in the Assessment of PFAS

Barbara Wetmore, US EPA/CCTE

10:05 AM–10:35 AM

Scientific Program Break—Attendee Small Group Discussion

10:35 AM–11:00 AM

Application of High-Throughput Exposure Modeling in Risk-Based Prioritization for PFAS 

Caroline Ring, ToxStrategies, Inc.

11:00 AM–12:00 Noon

Moderated Panel Discussion 

All speakers +

Erik Olson, National Resources Defense Council
Steve Via, American Waterworks Association
Jane Luxton, Lewis Brisbois LLC

12:00 Noon–12:30 PM

Special Session: What Evidence Sustains Health and Safety Regulations?

Gio Batta Gori, Health Policy Center

12:30 PM–1:30 PM

Attendee Luncheon
(Included with Registration)

1:30 PM–5:00 PM

Session: An Evolution of Risk Assessment for Potential Carcinogens in Food—Has the Time Arrived?

Moderator: Craig Llewellyn, Toxicology Regulatory Services

1:30 PM–2:00 PM

Carcinogenic Assessment of Substances in Food: Challenges, Potential Solutions, and Reality

Paul Hanlon, Abbott Nutrition

2:00 PM–2:30 PM

Has the End Arrived for the Bioassay and Why?

Jay Goodman, Michigan State University

2:30 PM–3:00 PM

Regulatory Perspective on Advances in Understanding Carcinogenicity of Substances Found in Food

Suzanne Fitzpatrick, US FDA/CFSAN

3:00 PM–3:30 PM

Scientific Program Break—Attendee Small Group Discussion

3:30 PM–4:00 PM

Incorporating Varying Levels of Data into Carcinogenicity Assessments in FEMA GRAS Expert Panel Determinations

Samuel Cohen, University of Nebraska Medical Center

4:00 PM–4:30 PM

Making the Case for In Vitro and In Silico Data for Assessing Carcinogenic Potential Substances: Challenges and Understanding the Data

Maureen Gwinn, US EPA/CCTE

4:30 PM–5:00 PM

Moderated Panel and Attendee Discussion

All speakers 

5:00 PM–5:15 PM

Introduction and Highlights of a Toxicology Forum Workshop on Carcinogen Risk Assessment—Fall 2020


Susan Felter, Procter & Gamble Company
Ed Ohanian, US EPA

5:30 PM–6:30 PM Welcome Reception


Tuesday, January 28


8:00 AM–12:00 Noon

Session: High-Throughput Screening Data and Use of Other In Vitro NAMs in Toxicological Evaluations—Advances, Opportunities, and Challenges 20 Years into the 21st Century


Grace Chappell, ToxStrategies, Inc
Tracy Chen, US FDA

8:05 AM–8:30 AM

Overview of the US EPA Computational Toxicology Dashboard and ToxCast/Tox21 Screening Program Data: Tools for Users

Katie Paul-Friedman, US EPA/CCTE

8:30 AM–9:00 AM

A Regulatory Perspective on Application of High-Throughput Screening (HTS) Data in Risk Assessment: Derivation of Toxicity Values Using HTS Data

Jason Lambert, US EPA/NCEA

9:00 AM–9:30 AM

Use of High-Throughput Transcriptomics for Characterizing Chemical Effects in Biological Systems

Scott Auerbach, NIEHS/NTP

9:30 AM–10:00 AM

The Brave New World: Challenges and Opportunities for Industry Use of High-Throughput and High-Content Screening Data for Safety Assessments

Rick Becker, American Chemistry Council

10:00 AM–10:30 AM Scientific Program Break—Attendee Small Group Discussion
10:30 AM–11:00 AM

In Vitro New Approach Methodologies following Prioritization Using High-Throughput Screening Data—Challenges, Validation, and Uses of Tissue Chip Technology

Courtney Sakolish, Texas A&M University

11:00 AM–12:00 Noon

Moderated Panel and Attendee Discussion

Includes all invited speakers

12:00 Noon–12:30 PM

Philippe Shubik Memorial Award Lecture

12:30 PM–1:30 PM Attendee Luncheon
(Included with registration)
1:30 PM–3:30 PM

Session: Update to the Cramer et al., Decision Tree and Thresholds of Toxicological Concern to Improve Safety Assessment and Prioritize Chemicals for Testing

Moderator: Kirk Arvidson, US FDA/CFSAN

1:30 PM–1:35 PM

Introduction to the Session  Downloads ALL Presentations in Session

Kirk Arvidson, US FDA/CFSAN

1:35 PM–1:45 PM

History of the Cramer et al., Decision Tree and the Threshold of Toxicological Concern

Renata Kolanos, US FDA

1:45 PM–2:15 PM

Updates to the Cramer et al., Decision Tree and the Threshold of Toxicological Concern: The Expanded Decision Tree 

Szabina Stice, US FDA/CFSAN

2:15 PM–2:45 PM

Application of the Expanded Decision Tree and Updated Threshold of Toxicological Concern to Safety Assessment  

Timothy Adams, US FDA/CFSAN

2:45 PM–3:00 PM

Codex Alimentarius: Guidelines for Rapid Risk Analysis following Instances of Detection of Contaminants in Food Where There Is No Regulatory Level

Lauren Robin (Posnick), US FDA

3:00 PM–3:30 PM

Moderated Panel and Attendee Discussion

All speakers 

3:30 PM–4:00 PM Scientific Program Break—Attendee Small Group Discussion
4:00 PM–4:30 PM

Update: New Data Requirements for Sunscreen Over the Counter Actives—Challenges and Opportunities

Sarah Vater, ToxStrategies, Inc.

4:30 PM–5:00 PM

Update: Whither the Safe Dose for Perfluorooctanoate (PFOA)?

Michael Dourson, Toxicology Excellence for Risk Assessment

5:30 PM–6:30 PM Attendee Reception
(Included with Registration) 


Wednesday, January 29


8:00 AM–10:00 A
8:00 AM–10:00 AM

Session: Advances in Thresholds of Toxicological Concern (TTC): Expansion of Databases to Support New Chemical Space


Susan Borghoff, ToxStrategies, Inc.
Susan Felter, Procter & Gamble Company

8:00 AM–8:15 AM

Applicability of TTC Across Chemical Space: What’s In and What’s Out

Susan Felter, Procter & Gamble Company

8:15 AM–8:40 AM

Update on Cramer Class II  

Anne Marie Api, Research Institute for Fragrance Materials

8:40 AM–9:05 AM

Case Study: Application of the TTC Approach to the Risk Assessment of Organosilicone Substances

Jane Rose, Procter & Gamble Company

9:05 AM–9:30 AM

TTC for Per- and Poly-fluoroalkyl Substances (PFAS), Applicability and Enrichment of Chemical Space

Ly Ly Pham, ToxStrategies, Inc.

9:30 AM–10:00 AM

Moderated Panel and Attendee Discussion

All speakers +

Timothy Adams, US FDA/CFSAN
Szabina Stice, US FDA/CFSAN

10:00 AM–10:30 AM Scientific Program Break—Attendee Small Group Discussion
10:30 AM–2:15 PM

Session: Electronic Nicotine Delivery System (ENDS) Toxicity: Knowns and Unknowns


Susan Chemerynski, US FDA/CTP
A. Wallace Hayes, University of South Florida

10:30 AM–11:00 AM

Toxicity of E-cigarettes: Research Highlights and Data Gaps

Cissy Li, US FDA

11:00 AM–11:30 AM

Tobacco Product Surveillance and Emerging Health Issues

Anna-Sophie Weidner, US FDA

11:30 AM–12:00 Noon

From Lab Bench to Clinic Bedside: Investigating Inhalation Toxicity of E-cigarettes

Maciej Goniewicz, Roswell Park Comprehensive Cancer Center

12:00 Noon–12:30 PM Scientific Program Break—Attendee Small Group Discussion
12:30 PM–1:00 PM

Industry Perspective on E-cigarettes

Julia Hoeng, Phillip Morris International

1:00 PM–1:15 PM

The Importance of Tobacco Toxicological Data and Analysis

Matthew Holman, US FDA/CTP

1:15 PM–2:15 PM

Moderated Panel and Attendee Discussion

All speakers +

Matthew Holman, US FDA/CTP